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24-hour intraocular pressure monitoring

Eye Care ≈ ¥200-500 (≈ $30-70) 24 hr

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Description

Estimated cost for 24-hour intraocular pressure monitoring at general public hospitals in China is about ¥140-400, and at Grade 3A hospitals about ¥200-500, varying by hospital tier and region.

Main Uses

24-hour intraocular pressure monitoring is primarily used to detect masked or nocturnal IOP elevations undetectable during standard office visits, assess diurnal IOP patterns and fluctuations in glaucoma suspects and diagnosed patients, evaluate treatment efficacy (e.g., timing of medication dosing), guide surgical decision-making (e.g., candidacy for minimally invasive glaucoma surgery), and differentiate normal-tension glaucoma from other optic neuropathies. It is especially indicated in progressive glaucomatous damage despite 'controlled' office IOP, suspected nonglaucomatous optic nerve cupping, and preoperative risk stratification for high-risk patients.

Normal Range

In healthy adults, intraocular pressure (IOP) typically ranges from 10 to 21 mmHg. During 24-hour monitoring, the normal diurnal variation is usually ≤6 mmHg, with peak IOP commonly occurring between 2 AM and 8 AM and trough values in the late afternoon (4–6 PM). Mean 24-hour IOP is generally 13–17 mmHg; values consistently >21 mmHg or showing abnormal circadian pattern (e.g., nocturnal acrophase, excessive fluctuation >8 mmHg) are considered abnormal.

Low Values - Possible Causes

Hypotony (IOP <5 mmHg) may result from: 1) Post-surgical complications (e.g., bleb leak after trabeculectomy), 2) Chronic uveitis with ciliary body suppression, 3) Retinal detachment causing reduced aqueous production, 4) Ocular trauma with cyclodialysis cleft, 5) Severe systemic hypotension or shock impairing ciliary perfusion.

High Values - Possible Causes

Elevated or abnormally patterned IOP may be caused by: 1) Primary open-angle glaucoma (POAG) with impaired aqueous outflow, 2) Normal-tension glaucoma (NTG) exhibiting pathological nocturnal IOP spikes despite daytime readings within 'normal' range, 3) Angle-closure glaucoma (especially intermittent or plateau iris configuration), 4) Steroid-induced ocular hypertension, 5) Obstructive sleep apnea (OSA)-associated nocturnal IOP elevation due to hypoxia and increased episcleral venous pressure.

24-hour intraocular pressure monitoring glaucoma diagnostic test IOP fluctuation assessment

≈ ¥200-500

≈ $30-70

Duration: 24 hr