Bone Marrow Aspiration and Biopsy
Health Checkups
≈ ¥200-500
(≈ $30-70)
15 min
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Description
Estimated cost for Bone Marrow Aspiration and Biopsy at general public hospitals in China is about ¥140-400, and at Grade 3A hospitals about ¥200-500, varying by hospital tier and region.
Main Uses
Bone marrow aspiration and biopsy are primarily used for diagnosing and monitoring hematological malignancies like leukemia, lymphoma, and multiple myeloma. They are also crucial for evaluating unexplained cytopenias, assessing the extent of metastatic cancer, and investigating storage diseases or other bone marrow infiltrative processes. Additionally, these procedures help in staging and follow-up of hematologic cancers, and in guiding treatment decisions.
Normal Range
The normal range for bone marrow aspiration and biopsy varies based on the specific indicators being tested. Commonly, a healthy bone marrow will show a balanced ratio of myeloid to erythroid (M:E) cells, typically around 2-4:1, with less than 5% blasts, and adequate megakaryocytes. The cellular composition should reflect the patient's age and hematopoietic needs.
Low Values - Possible Causes
Low values or abnormalities in bone marrow can be caused by aplastic anemia, where there is a failure of the bone marrow to produce sufficient blood cells; hypoplastic anemia, characterized by a decrease in all types of blood-forming cells; certain infections that affect bone marrow function; and exposure to radiation or chemotherapy which can suppress bone marrow activity.
High Values - Possible Causes
High values or abnormal findings in bone marrow tests may indicate conditions such as leukemia, where there is an increase in blast cells; myelodysplastic syndromes, leading to ineffective hematopoiesis and increased immature cell forms; polycythemia vera, causing an overproduction of red blood cells; and other myeloproliferative disorders that result in excessive production of one or more types of blood cells.