N-Acetyl-beta-D-glucosaminidase (NAG)
Laboratory Tests
≈ ¥20-50
(≈ $3-7)
15 min
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Description
Estimated cost for N-Acetyl-beta-D-glucosaminidase (NAG) at general public hospitals in China is about ¥15-40, and at Grade 3A hospitals about ¥20-50, varying by hospital tier and region.
Main Uses
The primary purpose of measuring N-Acetyl-β-D-Glucosaminidase (NAG) in urine is to assess early signs of kidney damage, particularly in the proximal tubules. It is useful in diagnosing and monitoring various forms of nephropathy, including drug-induced, diabetic, and hypertensive nephropathies. Additionally, it helps in evaluating the effectiveness of treatments aimed at preserving kidney function.
Normal Range
The normal range for N-Acetyl-β-D-Glucosaminidase (NAG) in urine is typically between 0.3 and 2.5 U/L, though this can vary slightly depending on the laboratory and the specific method used for measurement.
Low Values - Possible Causes
Low values of NAG in urine are less commonly a concern but may be associated with: decreased renal tubular function, certain medications that reduce enzyme activity, or very rarely, genetic deficiencies affecting NAG production.
High Values - Possible Causes
High values of NAG in urine can indicate: acute kidney injury, chronic kidney disease, interstitial nephritis, heavy metal toxicity, or urinary tract infections. These conditions lead to increased release of NAG from damaged renal tubules into the urine.