泪液分泌试验（Schirmer I试验）
眼科项目
≈ ¥20-50
(≈ $3-7)
大约15-30分钟
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项目介绍
泪液分泌试验（Schirmer I试验）在一般公立医院参考费用约¥15-40，三甲医院参考费用约¥20-50，常用于相关诊断评估与就医安排，费用随医院及地区有所差异。
主要用途
Primary diagnostic tool for evaluating aqueous-deficient dry eye disease; screening and monitoring severity in Sjögren’s syndrome and other autoimmune lacrimal insufficiencies; preoperative assessment for refractive or cataract surgery to identify dry eye risk; differential diagnosis between aqueous-deficient and evaporative dry eye subtypes (often combined with tear film break-up time and meibomian gland evaluation); and objective documentation of tear production impairment in clinical trials and longitudinal management.
正常值范围
Schirmer I test measures baseline (unstimulated) tear production over 5 minutes using a standardized filter paper strip. Normal value: ≥10 mm of wetting in 5 minutes. Values 5–9 mm indicate mild to moderate aqueous tear deficiency; <5 mm indicates severe deficiency. Age- and gender-adjusted norms apply: healthy adults typically produce 10–15 mm; older adults (>65 years) may average 8–12 mm; females often show slightly lower values than males.
偏低可能原因
Sjögren’s syndrome, aging-related lacrimal gland dysfunction, chronic blepharitis or meibomian gland dysfunction (secondary aqueous deficiency), systemic autoimmune diseases (e.g., rheumatoid arthritis, systemic lupus erythematosus), long-term contact lens wear, certain medications (e.g., anticholinergics, antidepressants, antihistamines, beta-blockers), radiation therapy to the head/neck, and idiopathic dry eye.
偏高可能原因
Reflex hypersecretion due to ocular surface irritation (e.g., corneal abrasion, foreign body, trichiasis, allergic conjunctivitis), acute bacterial or viral conjunctivitis, exposure keratopathy (e.g., lagophthalmos, facial nerve palsy), post-surgical inflammation (e.g., after LASIK or cataract surgery), and environmental triggers (e.g., wind, smoke, low humidity causing compensatory tearing). Note: Schirmer I is not designed to assess reflex tearing; high values are uncommon and usually reflect confounding irritative stimuli rather than true hyperlacrimation.